Designing or modifying proteins has wide application in drug design, materials design, and enzyme design for low-energy manufacturing. In recent years, computational protein design (CPD) techniques for molecular simulation have been used to predict sequences with new and improved functions. However, CPD involves astronomically large search problems, rapidly exceeding the capabilities of even the largest supercomputers. Using a classical-quantum hybrid approach on a D-Wave system, Menten achieved better solutions, faster, compared to a classical computer.